Diet and dieting behavior

# Which diet is better for you? Diets have been referred to as a special type of diet since the time of the ancient Greeks. A diet was not only understood to be a way of eating, but also a healthy lifestyle. Nowadays, the term diet is reserved exclusively for nutritional measures that in many cases aim to achieve weight loss and promote well-being in the broadest sense. There is a wide variety of diets, with the most popular at the moment being the low carb diet, the Paleo diet or the Mediterranean diet. The success of such diets depends not only on the chosen method, but also on the individual's physical and genetic disposition and lifestyle. Genetics plays an important role in the regulation of metabolism and influences how our body absorbs, processes and stores nutrients. It stands to reason that certain genetic variations can also have an impact on the success of various dietary measures. > ## Good to know > > Regardless of your genetic predisposition, long-term weight loss can be achieved with a type-appropriate change in diet and an individual exercise program. In any case, consistency and discipline are required. # The future lies in personalized nutrition Genetics and its influence on nutrition have increasingly attracted the interest of scientists in recent years. The idea that our genetic makeup can influence our diet is fascinating and has driven the research field of personalized nutrition. Although genetics undoubtedly plays an important role in our response to food, it should only be understood as part of the overall picture. Other factors such as lifestyle, exercise, eating and drinking habits, social environment, etc. influence the response to diets and dieting behavior in equal measure. # What do genetics have to do with it? We are investigating two genes with regard to your reaction to diets and your dieting behavior: Both genes examined show correlations with the effectiveness of a high protein diet and a high carb/low fat diet. The C2CD3 gene (C2 Domain Containing 3 Centriole Elongation Regulator gene) is involved, among other things, in the formation of so-called cilia. These are thin projections on the surface of almost all cells in the human body for the purpose of locomotion of the cell or for the uptake of signals from the environment - Variant rs1800849 of the C2CD3 gene: Genotypes A/A and A/G show less weight loss on a high protein diet and no improvement in LDL cholesterol levels, blood sugar levels or insulin levels. - Variant rs1800849 of the C2CD3 gene: The G/G genotype shows a good metabolic response, including weight loss, on a high protein diet. The FUT1 gene (alpha-1,2-fucosyltransferase gene) carries the blueprint for the enzyme fucosyltransferase 1 in the cells, which is involved in the formation of blood group antigens. Mutations in the FUT1 gene influence the production of the enzyme and often lead to the inadequate formation of certain blood group antigens. - Variant rs838147 of the FUT1 gene: Genotypes A/G and G/G show good results, including weight loss, when following a low-calorie high carb/low fat diet.